Contraindications (a condition which makes a particular treatment or procedure possibly inadvisable):

  • Allergy to any of the additives
  • Anemia
  • End stage Renal disease
  • G6PD deficiency
  • Uncontrolled serum glucose above 300 mg/dL (16.7 mmol/L)


  • Cardiac arrhythimias
  • Decreased renal function
  • Metal storage diseases: In the presence of hemochromatosis or Wilson disease, regular monitoring is recommended. Exacerbation of those conditions might necessitate discontinuation of IV C.
  • Iron overload because of a history of frequent transfusion.